Michael Balfour may refer to:

• Michael Balfour (historian), English historian and civil servant
• Michael Balfour, 1st Lord Balfour of Burleigh (died 1619), Scottish peer
• Sir Michael Balfour, 4th Baronet (died 1698) of the Balfour baronets
• Sir Michael Balfour, 5th Baronet (died 1709) of the Balfour baronets
• Sir Michael Balfour, 6th Baronet (died 1750) of the Balfour baronets
• Michael Balfour (actor) (1918–1997), English actor in The Krays film